学术成果与获奖情况
在《Molecular and Cellular Endocrinology》、《Cancer Science》、《Journal of Hepatology》、《International Journal of Cancer》、《Biochemical and Biophysical Research Communications 》等国内外刊物发表SCI论文和综述40余篇。代表性论文:1、Yuan H, Hu Y, Zhu Y, Zhang Y, Luo C, Li Z, Wen T, Zhuang W, Zou J, Hong L, Zhang X, Hisatome I, Yamamoto T, Cheng J. Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells. Mol Cell Endocrinol. Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells. Mol Cell Endocrinol,2017,443:138-145.
2、Zou J, Hong L, Luo C, Li Z, Zhu Y, Huang T, Zhang Y, Yuan H, Hu Y, Wen T, Zhuang W, Cai B, Zhang X, Huang J, Cheng J. Metformin inhibits estrogen-dependent endometrial cancer cell growth by activating the AMPK-FOXO1 signal pathway. Cancer Sci,2016,107(12):1806-1817. 3、程継東, 山本哲也. 無症候性高尿酸血症の治療-糖尿病の合併について.高尿酸血症と痛風,2016,24(1):56-60. 4、Zhu Y, Hu Y, Huang T, Zhang Y, Li Z, Luo C, Luo Y, Yuan H, Hisatome I, Yamamoto T, Cheng J. High uric acid directly inhibits insulin signalling and induces insulin resistance. Biochem Biophys Res Commun,2014,447:707-714. 5、Cheng J, Imanishi H, Morisaki H, Liu W, Nakamura H, Morisaki T, Hada T. Recombinant HbsAg inhibits LPS-induced COX-2 expression and IL-18 production by interfering with the NF kappa B pathway in a human monocytic cell line, THP-1. J Hepatol,2005,43:465-471. 获奖情况:曾获兵库医科大学大学院学術赏(2003年)、AstraZeneca研究奖励赏(2007年)、汕头市科学技术奖一等奖(2016年)等奖项。